Georges Rasetti was a student of the French painter and educator Léon Bonnat in addition, Rasetti was also a student of artist Florent Willems.
Rasetti exhibited at the Salon many times. In 1877, Rasetti exhibited a large canvas entitled David continued by Séméï at the Paris Salon. In 1878, he presented a painting titled La Fagotière de Samois. In 1879, he presented a painting titled Le Chapelet, winning a mention. In 1880 and 1881, Rasetti presented portraits at the Paris Salon; at the same time, he began to produce etchings, including one published in L'Union littéraire des poètes et des prosateurs.
In the fall of 1888, Rasetti met Paul Gauguin, which helped him to break with realism and meet the future Les Nabis. Gauguin was a French Post-Impressionist artist. Unappreciated until after his death, Gauguin is now recognized for his experimental use of color and Synthetist style that were distinct from Impressionism. Rasetti's brother in law, Georges Alfred Chaudet, was a painter, photographer and art dealer for Paul Gauguin until Chaudet's death. He was a member of the group of painters known as the Pont-Aven School.
During the summer of 1891, Rasetti and his wife Céline Chaudet went to Brittany, a region in northwestern France. There, he spent time with his friends, artist Paul Sérusier, a French painter who was a pioneer of abstract art and an inspiration for the avant-garde Nabis movement, Synthetism and Cloisonnism; artist Jan Verkade, a Dutch Post-Impressionist and Christian Symbolist painter; and artist Mogens Ballin, a Danish artist and silversmith. Rasetti introduced them to painting on ceramics.
Rasetti's son, Georges Estrel Rasetti, participated in the painting event in the art competition at the 1928 Summer Olympics. Georges Estrel Rasetti's work, titled Cross-Country, was an 80 cm tall oil-on-canvas painting featuring football players.In addition, Georges Estrel Rasetti also participated in the painting event in the art competition at the 1924 Summer Olympics in Paris, France.